GARP Risk Review

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چکیده

Without question, the adoption of FAS 133 will have an impact on the way firms use derivatives. One application that will certainly be affected is the use of currency swaps in conjunction with funding in a currency other than the functional currency. In the past, synthetic instrument accounting ruled. Under that regime, the accounting did not distinguish between issuing fixed rate debt directly and using derivatives to achieve the same goal. In certain cases, the synthetic instrument result may still be achieved, or at least approximated; but not always.

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Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer

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How Soluble GARP Enhances TGFβ Activation

GARP (glycoprotein A repetitions predominant) is a cell surface receptor on regulatory T-lymphocytes, platelets, hepatic stellate cells and certain cancer cells. Its described function is the binding and accommodation of latent TGFβ (transforming growth factor), before the activation and release of the mature cytokine. For regulatory T cells it was shown that a knockdown of GARP or a treatment ...

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تاریخ انتشار 2002